Pore-forming toxins (PFTs) produced by sea anemones, most notably the actinoporins, represent a fascinating class of proteins that disrupt target cell membranes through the formation of transmembrane ...

Future Microbiol. 2013;8(1):73-84. Work in the Mulvey laboratory is supported by NIH grants AI095647, AI090369 and AI088086. TJ Wiles was funded by NIH Genetics Training Grant T32-GM007464. The ...

Blocking calcium entry or the MAPK relay was enough to stop every downstream response. Breathing in the duo drives classic allergy signs in mice, with eosinophils in the lungs, T-helper-2 cells, and ...

Six years ago, researchers described the first toxin ever found for the deadly pathogen Mycobacterium tuberculosis. However, the mechanism for its secretion from the bacterium was unknown. Now, ...