Prof. Liu Cong from the Shanghai Institute of Organic Chemistry of the Chinese Academy of Sciences, along with collaborators, ...

Cryogenic electron microscopy (cryo-EM) is a variant of electron microscopy that uses cryogenically cooled samples that have been ‘flash frozen’. Cryo-EM methods have proved revolutionary in the life ...

Structure-based designs facilitate drug discovery, and cryogenic electron microscopy (cryo-EM) is an increasingly important tool to determine high-resolution structures of proteins and protein ...

Getting a detailed look at human proteins is often key to designing drugs that target them. For decades, drug developers have typically relied on X-ray crystallography for that purpose—a technique ...