Early thymic progenitor (ETP) cells, derived from hematopoietic stem cells in the bone marrow, enter the thymus at the cortical-medullary junction (CMJ), retaining multipotent differentiation ...

The axolotl, a type of salamander that stays in the tadpole form throughout its life, is a master of regeneration. Axolotls have been observed to regrow several body parts, including limbs, eyes, and ...

Tolerance Bio’s Implanted iPSC-derived Thymic Organoids Enable In Vivo Positive Selection of Human T cells and Tumor Burden Reduction in Melanoma Patient-specific human immune system-bearing mouse ...

BERLIN — The health of a cancer patient’s thymus could be linked to survival outcomes with immunotherapy, regardless of the tumor type and independent of established tumor-based biomarkers, suggests ...

The health of the thymus - a key part of the body's immune system - is associated with cancer patients' outcomes to immune checkpoint inhibitor treatment, according to a ground-breaking international ...

Johns Hopkins Medicine Associate Professor Giorgio Raimondi, PhD. is this week's MMI Thursday Seminar speaker. Please join us for this week's MMI Thursday Seminar: Engineering Thymic Selection Takes ...

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Thymocytes are generated, selected and mature in the thymus to create a diverse, functional and self-tolerant T cell repertoire. Selection of thymocytes relies on the level of their T cell receptor ...